Antioxidant and anti-inflammatory properties of essential oils from three Eucalyptus species

Abstract Eucalyptus essential oils are used as traditional medicines in many countries. The objective of this study was to evaluate the antioxidant and anti-inflammatory activities leaf extracted from three different species on HepG2 RAW264.7 cells. Essential were distilled fresh samples, chemical constituents analyzed using gas chromatography–mass spectrometry. determined ABTS hydroxyl radical scavenging assays, hydrogen peroxide (H2O2)-induced oxidative stress Additionally, lipopolysaccharide (LPS)-activated macrophages properties. results revealed that citriodora urophylla had a high content oxygenated monoterpenes, whereas deglupta contained amount monoterpene hydrocarbons. showed activities. E. strong activity against H2O2-induced human oil, which contains citronellal, exhibited most potent LPS-activated macrophages. effects depended their composition. A principal component analysis explained 100% variance performed construct groups based components This suggests represents good source could be considered potential phytochemical agent for prevention inflammation. Keywords: Antioxidant, Anti-inflammatory effect, oils, Gas spectrometry, Principal